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Ali VelshiCanadian journalist

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Ali Velshi (born October 29, or ) is a Canadian television journalist, a senior economic and business correspondent for NBC News since October and co-anchor with Stephanie Ruhle of Velshi & Ruhle on MSNBC. Velshi is based in New York City. Known for his work on CNN, he was CNN's Chief Business Correspondent, Anchor of CNN's Your Money and a co-host of CNN International's weekday business show World Business Today. In , he joined Al Jazeera America, a channel that launched in August of that year. He hosted Ali Velshi on Target until Al Jazeera America ceased operations on April 12, He has worked for MSNBC since October

Area of Study / Keywords

EpigeneticsBreast cancerPaediatric cancerNeurodevelopmental disordersChromatin biologyHistone modifications

About

Dr. Alan Underhill is currently appointed as Associate Professor in the Department of Oncology in the Faculty of Medicine & Dentistry.

Research

The Underhill laboratory is interested in deciphering how histone modifications regulate genome structure and function, and their alteration in disease.

Epigenetic control in development and cancer

An essential component in the management and functional output of eukaryotic genomes is that their DNA is assembled into chromatin via the formation of nucleosomes, which comprise bp of DNA wrapped nearly twice around an octamer of the core histone proteins H2A, H2B, H3, and H4 in equal stoichiometry. In addition to providing a means to compact the genome so that it fits within the confines of the nucleus, chromatin serves diverse roles in facilitating expression, repression,