Jaye rudolph biography sample
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Published in final edited form as: J Am Chem Soc. 2008 Jan 8;130(4):1227–1235. doi: 10.1021/ja0754507
Abstract
The neutral form of the chromophore in wild-type green fluorescent protein (wtGFP) undergoes excited state proton transfer (ESPT) upon excitation, resulting in characteristic green (508 nm) fluorescence. This ESPT reaction involves a proton relay from the phenol hydroxyl of the chromophore to the ionized side chain of E222, and results in formation of the anionic chromophore in a protein environment optimized for the neutral species (the I* state). Reorientation or replacement of E222, as occurs in the S65T and E222Q GFP mutants, disables the ESPT reaction and results in loss of green emission following excitation of the neutral chromophore. Previously, it has been shown that the introduction of a second mutation (H148D) into S65T GFP allows the recovery of green emission, implying that ESPT is again possible. A simil
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Tick, Tick... Boom!
Musical by Jonathan Larson
"Tick ljud av klocka Boom" redirects here. For the single by The Hives, see Tick ljud av klocka Boom (song). For the film adaptation, see ljud av klocka, Tick... Boom! (film).
Tick, ljud av klocka. Boom! (styled as tick, tick... BOOM!) is a musical bygd Jonathan Larson. It tells the story of an aspiring composer named Jon, who lives in New York City in 1990. Jon fryst vatten worried he has made the wrong career choice to be part of the performing arts. The story fryst vatten semi-autobiographical, as stated bygd Larson's father in the liner notes of the cast recording – Larson had been trying to establish han själv in theater since the early 1980s.
Larson began to perform the del av helhet as a solo work in 1990. After his death in 1996, it was revised and revamped by playwright David Auburn as a three-actor del av helhet and was premiered Off-Broadway in 2001.[1] Since then, the show has had an Off West End production, a West End production, an American national tour, two Off-Broadway revi
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The Scottish Simulation ‘KSDP’ Design Framework: a sense-making and ordered approach for building aligned simulation programmes
- Innovation
- Open access
- Published:
Advances in Simulationvolume 9, Article number: 52 (2024) Cite this article
Abstract
Impactful learning through simulation-based education involves effective planning and design. This can be a complex process requiring educators to master a varied toolkit of analysis tools, learning methodologies, and evaluative strategies; all to ensure engagement of learners in a meaningful and impactful way. Where there is a lack of thoughtful design, simulation-based education programmes may be inefficiently deployed at best, and completely ineffective or even harmful to learning and learners at worst. This paper presents a useful sense-making framework, designed to support simulation educators in designing their learning activities in a systematic, stepwise, and learner centred way.
Embedding simulation programmes