Ara papain biography of rory
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Abstract
The potential emergence of SARS-CoV-2 variants capable of escaping vaccine-generated immune responses poses a looming threat to vaccination efforts and will likely prolong the duration of the COVID pandemic. Additionally, the prevalence of beta coronaviruses circulating in animals and the precedent they have set in jumping into human populations indicates that they pose a continuous threat for future pandemics. Currently, only one therapeutic is approved by the U.S. Food and Drug Administration (FDA) for use in treating COVID, remdesivir, although other therapies are authorized for emergency use due to this pandemic being a public health emergency. In this review, twenty-four different treatments are discussed regarding their use against COVID and any potential future coronavirus-associated illnesses. Their traditional use, mechanism of action against COVID, and efficacy in clinical trials are assessed. Six treatments evaluated are shown to significantly decrease mortality
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Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
Introduction
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and cause outbreaks worldwide. Antibody-mediated immunity established via natural infection or vaccination reduces the risk of disease or lessens the clinical severity of the infection1,2. Neutralizing antibody levels and spike-binding antibody levels serve as correlates of protection against SARS-CoV-2 in humans1,2. Although neutralizing antibodies are elicited against other parts of the spike protein, the receptor-binding domain (RBD) is the dominant target of the neutralizing antibody response3,4,5,6,7.
The antigenic characterization of the RBD by human neutralizing antibodies revealed four major antigenic sites, two of which (class 1 and class 2) are located at the top of RBD and overlap with the ACE2-binding site (or RBM, the receptor-binding motif), while the other two are o
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Biological and Health Sciences
Below are links to our archives of posters from Spring to our current semester as arranged by their content area. These are provided as examples of quality academic posters and presentations.
Fall
Registration is now underway until November 13, at 4pm. For more information, please visit the Fall Symposium page.
Spring
Biology
Methodological Challenges For Quantifying Grazing Among Mixotrophic Algae – Valerie Sleva – advisor: Dr. Sarah Princiotta
Potential Antibiotic Properties of 2,3-diphenyl-2,3-dihydro-1,3-thiazaones Elyssa Yeagley – advisor: Ms. Mary Ann Smith
The Phage Underground Scarlet Tejada Rodrieguez – advisor: Ms. Mary Ann Smith
Antibiotics around the World Haily Showers – advisor: Ms. Mary Ann Smith
The Bioinformatics of Gene Actbeta in Drosophila kikkawai Grace Carolonza – advisor: Ms. Mary Ann Smith
Support for Pollinators: Could Physical Attractiveness Play a Role? Logan Maurer – advisor: Dr. Brenna T